Everything should be enclosed in plastic because water is the enemy of every camper's gear. Ziploc bags are the best in my opinion. If rain is expected line the inside of the pack with a large trash bag then put the Ziplocked items in. Then put the pack cover over the pack. It may seem a bit extreme but soggy clothes can be uncomfortable and in winter weather hazardous.
Remove any excess air from the bags before closing them. This can be done by squeezing the bag and contents tightly before sealing. This is usually sufficient. It is possible to get even more air out by closing the bag most of the way and sucking the rest of the air out. To suck the air out you could use an air mattress inflator/deflator or a vacuum cleaner. Be careful not to pack too much. If you vacuum pack everything when you leave you may not be able to fit it all in once the bags are opened and their contents expand.
Typically a Ziploc bag will last three or more camp outs so don't throw them out. When you are finished unpacking after the trip put all the bags in your pack for next time.
When changing clothes use the empty bags from the clean clothes to store the used clothes in. This helps in at least two ways. First it keeps the used, possible wet (dry wet clothes first whenever possible) and/or dirty clothes from making a mess of anything else. Second in the event of the pack getting soaked the used clothing will still be dry. Dry clothes are lighter to carry.
Pack sets of clothes together. For instance put your shirt, socks and underwear in one bag. During the summer shorts may also fit in one bag. When it is time to find the clothes you only need to find one or two bags not the sock bag, underwear bag, shirt bag ...
Always pack you stuff the same way. Make a drawing of your pack. Mark it up with locations of your stuff. Every time you pack look at the drawing. Put a copy of the map in one of the outer pockets so you can refer to it if need be during the outing. After a while it will become second nature to where stuff goes and where to find it. You will probably update the map until you are happy with everything's location. While packing think about what order you will need things. Put items like extra clothes and spare shoes deep down in your pack leaving the more accessible areas for items you will definitely use.
Put your rain poncho, water bottles, first aid kit and flashlight in an easy to get to outer pocket.
Sleeping Bag Tips
Put your pajamas, sleeping socks and sleeping hat (if winter camping) up in your sleeping bag before you roll it up. This way they are available when it is time to bed down. Additionally they are not in your way when digging for other stuff in your pack. Even though these articles are being packed in your sleeping bag they should still be in bags to keep them dry in case your sleeping bag should get wet. Distribute them evenly so you sleeping bag still rolls up nicely.
Put your sleeping bag in a garbage bag to keep it dry. Don't tie a tight knot in the bag you put your sleeping bag in. It may be too difficult to get undone an you will have to tear the plastic to get the sleeping bag out. Which means you won't be able to reuse the plastic bag.
The dead air space between the filling of the sleeping bag is what keeps the warmth in. Rolling your sleeping bag really tight breaks down the filling or storing it stuffed as small a space as possible. Then the bag won't fluff up as much and not keep you as warm. When stowing it away between trips either roll it loose or and store folded it in plastic bin. The bin must have enough room to let the filling expand. In the same light you should lay your bag out in your tent as soon as reasonably possible when on an outing. Basic keep it rolled up tightly only when you are
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